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簡(jiǎn)要描述:An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodami
產(chǎn)品型號(hào):bsm-52821R
廠商性質(zhì):生產(chǎn)廠家
更新時(shí)間:2025-02-28
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